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Hydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigational[A192132] **The FDA emergency use authorization for hydroxychloroquine and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]
Synonyms: 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineProducts: PMS-hydroxychloroquineLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin was approved by the FDA on May 2, 2011[L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050
Categories: Drugs Used in DiabetesProducts: LINAGLIPTIN EGNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33714,L33719] Naloxone was granted FDA approval on 13 April 1971.[L33709] … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: PMS-buprenorphine-naloxone, PMS-buprenorphine-naloxoneSynonyms: 1-N-Allyl-14-hydroxynordihydromorphinoneFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, os...
Products: STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON, FLURBIPROFENE EG LABORATORI EUROGENERICICarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
Categories: Compounds used in a research, industrial, or household settingProducts: PLATINWAS 150 MG 10MG/ML ENJ. FLAKON, 1 ADET, PLATINWAS 450 MG 10MG/ML ENJ. FLAKON, 1 ADETBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigational[A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. … Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients.
Products: PMS-baclofen, PMS-BACLOFEN TABLET 10 mgDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Products: DOMPERIDONE EG, PMS-domperidoneLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide.
Mixtures: PMS-losartan-hctz, PMS-losartan-hctzCategories: Agents Acting on the Renin-Angiotensin SystemSennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalSennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery.
Mixtures: EX-lax Gentle Strength, Laxatif De Sene Et Docusate De SodiumProducts: Senna Gen, EX-lax Maximum Strength Stimulant LaxativeLormetazepam
go.drugbank.com/drugs/DB13872ApprovedLormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Synonyms: N-MethyllorazepamProducts: LORMETAZEPAM EG