Search

Displaying results 641 - 650 of 10000 in total
  1. Drug

    Anastrozole

    go.drugbank.com/drugs/DB01217
    ApprovedInvestigational

    as compared to earlier estrogen receptor modulators such as [tamoxifen]. … [A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863]

    Products: ANASTROZOLO EG
  2. Drug

    Indoramin

    go.drugbank.com/drugs/DB08950
    ApprovedWithdrawn

    Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese.

    International brands: Baratol
  3. Drug

    Sertraline

    go.drugbank.com/drugs/DB01104
    ApprovedInvestigational

    Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.

    Synonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineProducts: SERTRALINA EG, SERTRALINA EG STADA
  4. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic

    Mixtures: Enl, FERRITIN COMPLEXCategories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  5. Drug

    Everolimus

    go.drugbank.com/drugs/DB01590
    ApprovedInvestigational

    In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.

    Products: EVEROLIMUS EG
  6. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Mixtures: COMPLEJO B EN KOLA GRANULADA, COMPLEJO B EN KOLA GRANULADACategories: Vitamin B Complex
  7. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis.

    Mixtures: PIOGLITAZONE E METFORMINA EG, PIOGLITAZONE E METFORMINA EGCategories: Drugs Used in Diabetes
  8. Drug

    Clarithromycin

    go.drugbank.com/drugs/DB01211
    ApprovedInvestigational

    Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.

    Products: CLARITROMICINA EG, COMTRO
  9. Target

    Holliday junction branch migration complex subunit RuvB

    go.drugbank.com/bio_entities/BE0001514
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication … The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.

    Polypeptides: Holliday junction branch migration complex subunit RuvB
  10. Target

    Cytochrome b6-f complex iron-sulfur subunit

    go.drugbank.com/bio_entities/BE0002474
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex iron-sulfur subunit