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Gatifloxacin
go.drugbank.com/drugs/DB01044ApprovedInvestigationalWithdrawnGatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. … Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. It is also available as eye drops under the brand name Zymar® marketed by Allergan.
Categories: Topoisomerase II Inhibitors, Compounds used in a research, industrial, or household settingProducts: Tequin IVTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is currently under evaluation for the treatment of breast cancer, prostate cancer, in addition to pediatric sarcomas. Both the European Commission and the U.S. … Food and Drug Administration (FDA) have approved trabectedin as an orphan drug in soft tissue sarcomas and ovarian cancer.
Products: YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZSea salt
go.drugbank.com/drugs/DB11266ApprovedUnlike sea salt, table salt usually contains an additive to prevent clumping and involves addition of iodine. … In comparison, table salt is mined from underground sedimentary deposits and is more heavily processed to eliminate minerals.
Products: S Panax All In One LiquidsoapTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. … [A1489,A1490] Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.[A1492]
Mixtures: Van-telmisartan-hctz, Van-telmisartan-hctzCategories: Angiotensin II receptor antagonists, Angiotensin II Type 1 Receptor BlockersBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of somatotropin (growth hormone) secretion in some patients with acromegaly. … [L43942,L43947] It continues to be used for the indications mentioned above.
Categories: Adrenergic alpha-1 Receptor Agonists, Serotonin Receptor AgonistsProducts: BROMOCRIPTINE MESYLATE TABLETS USPSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].
Categories: DPP-IV Inhibitors, Drugs Used in DiabetesProducts: Instadip 25 (Sitagliptin Film Coated Tablets USP 25mg), Instadip 50 (Sitagliptin Film Coated Tablets USP 50mg)Loxapine
go.drugbank.com/drugs/DB00408ApprovedInvestigationalAn antipsychotic agent used in schizophrenia. [PubChem]
Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor AntagonistsProducts: Loxapac Im, Loxapine Hydrochloride Im Injection 50mg/mlMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational) receptor, and as an inhibitor of serotonin and norepinephrine uptake. … At higher doses, methadone use can result in respiratory depression, overdose, and death.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersProducts: Methadone Hydrochloride Oral Concentrate USPThyrotropin alfa
go.drugbank.com/drugs/DB00024ApprovedInvestigationalVet approvedIt is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues … The beta subunit (TSHB) bestows its receptor specificity due to the uniqueness to TSH. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.
Products: THYROGEN 0,9 MG/1,08 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 2 FLAKONTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.
Categories: Drugs Used in Benign Prostatic Hypertrophy, Adrenergic alpha-1 Receptor AntagonistsProducts: TAMSULOSIN ABZ 0.4MG R-KAP, TAMSULOSIN BASICS 0.4MG HK