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LYB014
go.drugbank.com/drugs/DB33993ExperimentalLYB014 is a biologic drug. LYB014 is under investigation in clinical trial NCT07831226 (Safety and Immunogenicity of the Recombinant Malaria Vaccines in Healthy Adults Aged 18-59 Years).
ALN-6457
go.drugbank.com/drugs/DB33986ExperimentalALN-6457 is a biologic drug. ALN-6457 is under investigation in clinical trial NCT07832370 (A Trial of ALN-6457 in Adult Participants With Symptomatic Prion Disease (PrD)).
ALT001
go.drugbank.com/drugs/DB33989ExperimentalALT001 is a biologic drug. ALT001 is under investigation in clinical trial NCT07833618 (A Phase II Study of ALT001 in Patients With Amyotrophic Lateral Sclerosis (ALS)).
Pimavanserin
go.drugbank.com/drugs/DB05316ApprovedInvestigationalIn fact, pimavanserin is the first antipsychotic drug without D<sub>2</sub> blocking activity. … [L48236] Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5-HT<sub>2A</sub> and HT<sub>2C</sub> receptors.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAmibegron
go.drugbank.com/drugs/DB05395InvestigationalAmibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Categories: Adrenergic beta-3 Receptor AgonistsMipomersen
go.drugbank.com/drugs/DB05528ApprovedMipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. … Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide.
Categories: Apolipoprotein B-100 Synthesis Inhibitor, Compounds used in a research, industrial, or household settingVerubulin
go.drugbank.com/drugs/DB05585InvestigationalAntineoplastic; a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
Categories: Heterocyclic Compounds, 2-RingFacinicline
go.drugbank.com/drugs/DB05586InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLarazotide
go.drugbank.com/drugs/DB05645InvestigationalAn octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
Synonyms: GLYCINE, GLYCYLGLYCYL-L-VALYL-L-LEUCYL-L-VALYL-L-GLUTAMINYL-L-PROLYL-, GLYCYLGLYCYL-L-VALYL-L-LEUCYL-L-VALYL-L-GLUTAMINYL-L-PROLYLGLYCINE