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Displaying results 6541 - 6550 of 10000 in total
  1. Drug

    BB-301

    go.drugbank.com/drugs/DB17011
    Investigational

    BB-301 is a modified AAV serotype 9 (AAV9) capsid expressing a unique, single bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 (PABPN1) and two small … [A260112] Developed by Benitec Biopharma, BB-301 is being investigated for the treatment of Oculopharyngeal Muscular Dystrophy (OPMD).[L47062]

  2. Drug

    Chelerythrine

    go.drugbank.com/drugs/DB17024
    Experimental

    A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.[A252982]

    Synonyms: 1,2-dimethoxy-12-methyl(1,3)dioxolo)4',5':4,5)benzo(1,2-c)phenanthridinium, (1,3)benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl-Categories: Heterocyclic Compounds, 3-Ring, Heterocyclic Compounds with 4 or More Rings
  3. Drug

    GBR-12879

    go.drugbank.com/drugs/DB17028
    Experimental

    Synonyms: 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine, Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propen-1-yl)-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Indatraline

    go.drugbank.com/drugs/DB17032
    Experimental

    Indatraline is a nonselective monoamine reuptake inhibitor.[A253022]

    Synonyms: (+/-)-trans-3-(3,4-dichlorophenyl)-n-methyl-1-indanamine
  5. Drug

    Dacinostat

    go.drugbank.com/drugs/DB17034
    Experimental

    Dacinostat is a novel histone deacetylase inhibitor.[A253032]

    Synonyms: (2e)-n-hydroxy-3-(4-(((2-hydroxyethyl)(2-(1h-indol-3-yl)ethyl)amino)methyl)phenyl)propenamide
  6. Drug

    PD-169316

    go.drugbank.com/drugs/DB17040
    Experimental

    PD-169316 is a p38 MAP kinase inhibitor.[A253062]

    Synonyms: 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole, Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)-Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    PD-173952

    go.drugbank.com/drugs/DB17041
    Experimental

    PD-173952 is a potent Myt1 kinase inhibitor.[A253067]

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    SB 224289

    go.drugbank.com/drugs/DB17052
    Experimental

    SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122]

    Synonyms: (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)methanone, 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro(2h-furo(2,3-f)indole-3(5h),4'-piperidine)Salts: SB 224289 hydrochloride
  9. Drug

    Spiperone

    go.drugbank.com/drugs/DB17056
    Experimental

    Spiperone is a dopamine antagonist that binds dopamine and serotonin receptors.[A253142]

  10. Drug

    TW-37

    go.drugbank.com/drugs/DB17059
    Experimental

    TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]

    Synonyms: Benzamide, n-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)-, N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)benzamide