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Displaying results 6561 - 6570 of 10000 in total
  1. Drug

    Magnesium oxide

    go.drugbank.com/drugs/DB01377
    ApprovedInvestigational

    Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.

    Mixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, Pregvit Folic 4Products: MAGNEZI KALSINE 100 G TOZ, 100 G, Magnesium 250 mg
  2. Target

    Phosphatidylinositol 4-kinase type 2-beta

    go.drugbank.com/bio_entities/BE0008985
    TargetHumans

    Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell (PubMed:11923287, PubMed:12324459). This contribution may be especially significant in plasma membrane, endosom...

    Polypeptides: Phosphatidylinositol 4-kinase type 2-betaSynonyms: Phosphatidylinositol 4-kinase type II-beta
  3. Target

    Taste receptor type 2 member 4

    go.drugbank.com/bio_entities/BE0020472
    TargetHumans

    Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.

    Polypeptides: Taste receptor type 2 member 4
  4. Target

    Neuropeptide Y receptor type 4-2

    go.drugbank.com/bio_entities/BE0024014
    TargetHumans

    The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13

    Polypeptides: Neuropeptide Y receptor type 4-2
  5. Drug

    Thiotepa

    go.drugbank.com/drugs/DB04572
    ApprovedInvestigational

    It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. … N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years.

    Synonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  6. Target

    Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

    go.drugbank.com/bio_entities/BE0000044
    TargetHumans

    Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity).

    Polypeptides: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingFunction: 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity
  7. Drug

    Granaticin B

    go.drugbank.com/drugs/DB17273
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: 8,11-ethanofuro(2,3-e)naphtho(2,3-c:6,7-c')dipyran-2,6,13(9h)-trione, 3,3a,5,8,11,13b-hexahydro-7,8,12-trihydroxy-5,9-dimethyl-15-(((2s,5s,6s)-tetrahydro-5-hydroxy-6-methyl-2h-pyran-2-yl)oxy)-, (3as,5s, Granaticin B
  8. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: LETARA® 2.5 MG TABLETAS, LETROZOL® 2.5 MG TABLETAS
  9. Target

    Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

    go.drugbank.com/bio_entities/BE0023607
    EnzymeHumans

    Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin, a step in the uric acid degradation pathway following urate oxidation (By similarity

    Polypeptides: Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylaseSynonyms: Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
  10. Drug

    Moexipril

    go.drugbank.com/drugs/DB00691
    ApprovedInvestigational

    Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension).

    Mixtures: UNIRETIC 15 MG/ 25 MG FILM KAPLI TABLET, 30 ADET, UNIRETIC 7,5 MG/ 12.5 MG FILM KAPLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring