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Displaying results 6581 - 6590 of 10000 in total
  1. Drug

    Nitroarginine

    go.drugbank.com/drugs/DB04223
    Investigational

    Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6) … An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity.

    Synonyms: N(gamma)-nitro-L-arginine
  2. Drug

    AVI-5126

    go.drugbank.com/drugs/DB05726
    Investigational

    AVI-526 is an improved formulation of [AVI-4557], developed for use on Vein Grafts before use in Heart by-Pass Graft Surgery. … The drug was under investigation in clinical trial NCT00451256 (Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)).

  3. Drug

    Oxyphenisatin

    go.drugbank.com/drugs/DB04823
    ApprovedWithdrawn

    It may cause jaundice.

    Categories: Drugs for Constipation
  4. Drug

    CDX-1135

    go.drugbank.com/drugs/DB17607
    Investigational

    It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage. … CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).

  5. Drug

    Solenopsis invicta

    go.drugbank.com/drugs/DB10419
    Approved

    Solenopsis invicta allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Insect Venom Allergenic Extract
  6. Drug

    Aureobasidium pullulans var. pullutans

    go.drugbank.com/drugs/DB10427
    Approved

    Aureobasidium pullulans var. pullutans is a fungus which can provoke allergic reactions. Aureobasidium pullulans var. pullutans extract is used in allergenic testing.

    Categories: Non-Standardized Fungal Allergenic Extract
  7. Drug

    Phoma exigua var. exigua

    go.drugbank.com/drugs/DB10440
    Approved

    Phoma exigua var. exigua is a fungus which can provoke allergic reactions. Phoma exigua var. exigua extract is used in allergenic testing.

    Categories: Non-Standardized Fungal Allergenic Extract
  8. Pathway

    mTOR Signaling pathway

    smpdb.ca/view/SMP0535455
    Signaling

    as rapamycin and its analogs—has shown efficacy in cancer and aging models but may also perturb immune function and metabolic homeostasis. … the Ragulator–Rag GTPase complex to promote RagA/B‑GTP formation and mTORC1 lysosomal localization; and glutamine activates mTORC1 via a Rag-independent mechanism requiring the Arf1 GTPase (and Rab1A in

    Drugs: Arginine · L-Glutamine · Leucine · ATP · Magnesium cation · Zinc
    Enzymes: Cytosolic arginine sensor for mTORC1 subunit 1
  9. Drug

    Aloe ferox leaf

    go.drugbank.com/drugs/DB14257
    Approved

    Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  10. Drug

    Heterotheca inuloides flower

    go.drugbank.com/drugs/DB14331
    Approved

    Heterotheca inuloides flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.