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Displaying results 651 - 660 of 10000 in total
  1. Drug

    Nisoldipine

    go.drugbank.com/drugs/DB00401
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.

    International brands: Ji Ni Le Er
  2. Drug

    Bacillus calmette-guerin substrain russian BCG-I live antigen

    go.drugbank.com/drugs/DB16648
    ApprovedInvestigational

    [L32734] It is to be marketed by Verity Pharmaceuticals, under the trade name VERITY-BCG, and manufactured by the Serum Institute of India. … Live BCG vaccines administered intravesically have been a gold standard therapy in the adjuvant treatment of non-muscle-invasive bladder cancers for decades,[A232264] used after tumor resection, and are

  3. Drug

    Indigofera tinctoria leaf

    go.drugbank.com/drugs/DB14314
    Investigational

    Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Qing Dai (Indigofera Tinctoria)
  4. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

    Categories: Analgesics, Non-Narcotic
  5. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [A245824] In addition, VLPs contain no viral material and are therefore inherently non-infectious, making them potentially safer alternatives to traditional vaccines.[A245824] … The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada

  6. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    It is identified by the symbol _Zn_ [L2098]. … Most recently, research has shown that polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 diabetes provided novel insights into the role of

    Mixtures: One A Day Tab, Vita Day TabSynonyms: Zn
  7. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    While about 90% of patients with newly diagnosed osteosarcoma may achieve complete remission from first-line therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower … NOD)-like receptors (NLRs) and toll-like receptors present in macrophages and monocytes.

  8. Pathway

    Acylcarnitine (2Z)-non-2-enoylcarnitine

    smpdb.ca/view/SMP0123414
    Metabolic

    (2Z)-non-2-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2Z)-non-2-enoyl-CoA reacts with L-carnitine to form (2Z)-non-2-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  9. Pathway

    Acylcarnitine (2E)-non-2-enedioylcarnitine

    smpdb.ca/view/SMP0123428
    Metabolic

    (2E)-non-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2E)-non-2-enedioyl-CoA reacts with L-carnitine to form (2E)-non-2-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Drug

    Nateglinide

    go.drugbank.com/drugs/DB00731
    Approved

    One minor metabolite, the isoprene, has the same potency as its parent compound. … Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).