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Displaying results 651 - 660 of 2256 in total
  1. Target

    Platelet-activating factor receptor

    go.drugbank.com/bio_entities/BE0005561
    TargetHumans

    Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system … Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity.

    Polypeptides: Platelet-activating factor receptorFunction: G protein-coupled purinergic nucleotide receptor activity
  2. Target

    Serine repeat antigen 5

    go.drugbank.com/bio_entities/BE0009196
    TargetPlasmodium falciparum

    Polypeptides: Serine repeat antigen 5
  3. Target

    Somatostatin receptor type 4

    go.drugbank.com/bio_entities/BE0009273
    TargetHumans

    Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

    Polypeptides: Somatostatin receptor type 4
  4. Target

    5-hydroxytryptamine receptor 3D

    go.drugbank.com/bio_entities/BE0009585
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: Serotonin receptor 3D
  5. Target

    Catecholate siderophore receptor Fiu

    go.drugbank.com/bio_entities/BE0009806
    TransporterEscherichia coli (strain K12)

    Receptor for microcins M, H47 and E492.

    Polypeptides: Catecholate siderophore receptor FiuSynonyms: TonB-dependent receptor Fiu
  6. Target

    Retinoic acid receptor RXR

    go.drugbank.com/bio_entities/BE0009978
    Target

  7. Target

    Toll-like receptor 6

    go.drugbank.com/bio_entities/BE0010079
    TargetHumans

    Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. … MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion (PubMed:11441107, PubMed:20037584)

    Polypeptides: Toll-like receptor 6
  8. Target

    Fibroblast growth factor receptor

    go.drugbank.com/bio_entities/BE0010259
    TargetHumans

    Over-expressed FGFR2 promotes activation of STAT1. … Over-expressed or constitutively activated FGFR3 promotes activation of PTPN11/SHP2, STAT1, STAT5A and STAT5B.

    Polypeptides: Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2Synonyms: Keratinocyte growth factor receptor, Basic fibroblast growth factor receptor 1
  9. Target

    Opioid growth factor receptor

    go.drugbank.com/bio_entities/BE0010541
    TargetHumans

    Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation

    Polypeptides: Opioid growth factor receptorSynonyms: Zeta-type opioid receptor
  10. Target

    Toll-like receptor 3

    go.drugbank.com/bio_entities/BE0010688
    TargetHumans

    Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response

    Polypeptides: Toll-like receptor 3