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Displaying results 6601 - 6610 of 10000 in total
  1. Drug

    Alipogene tiparvovec

    go.drugbank.com/drugs/DB13521
    Approved

    It is being investigated for the treatment of lipoprotein lipase (LPL) deficiency.[A259796, A259801, A259806, A259811] … Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers the Ser(447)X variant of the human lipoprotein lipase (LPL) gene.

  2. Drug

    Solcitinib

    go.drugbank.com/drugs/DB19856
    Investigational

    Solcitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Solcitinib is a Janus kinase inhibitor. … Solcitinib is under investigation in clinical trial NCT01777256 (An Adaptive Phase II Study to Evaluate the Efficacy, Pharmacodynamics, Safety and Tolerability of GSK2586184).

  3. Drug

    Fenticonazole

    go.drugbank.com/drugs/DB13434
    Investigational

    Fenticonazole has a broad spectrum of antimycotic activity against dermatophytes and yeasts.

  4. Drug

    Clonazoline

    go.drugbank.com/drugs/DB15881
    Experimental

    Clonazoline is

  5. Drug

    ChulaCov19 mRNA vaccine

    go.drugbank.com/drugs/DB16445
    Experimental

    The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678]. … The next phase of this study is for phase I and II clinical trials (NCT04566276) beginning in January 2021.

  6. Drug

    Penimepicycline

    go.drugbank.com/drugs/DB13264
    Experimental

    In the classification of the active ingredients included on this list, the classification document states that tetracycline class antibiotics are of medium importance, and are used in humans [L5620]. … Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients [L2791].

  7. Drug

    Trefentanil

    go.drugbank.com/drugs/DB09181
    Experimental

    Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research. … Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil.

  8. Drug

    Dimenoxadol

    go.drugbank.com/drugs/DB01461
    ExperimentalIllicit

    In the United States it is classified as a Schedule I controlled drug. … Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative.

  9. Drug

    Halofuginone

    go.drugbank.com/drugs/DB04866
    InvestigationalVet approved

    Halofuginone also effectively suppresses tumor progression and metastasis in mice. … Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S. Food and Drug Administration in March, 2000.

  10. Drug

    Gambir

    go.drugbank.com/drugs/DB14298
    Investigational

    Gambir is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.