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Varlitinib
go.drugbank.com/drugs/DB05944InvestigationalVarlitinib is an oral, selective, reversible, small molecule tyrosine kinase inhibitor of both ErbB-2 (Her-2/neu) and EGFR. Over-expression of ErbB-2 and EGFR receptors in tumors is predictive of poor prognosis in cancer patients. Varlit...
Filanesib
go.drugbank.com/drugs/DB06040InvestigationalFilanesib is a potent Kinesin Spindle Protein (KSP) inhibitor that caused marked tumor regression in preclinical models of human solid tumors and human leukemias, often leading to durable responses.
Mezigdomide
go.drugbank.com/drugs/DB17584Investigationalunder investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or
Lifarizine
go.drugbank.com/drugs/DB20533ExperimentalThe usage of the INN stem '-rizine' in the name indicates that Lifarizine is a antihistaminic/cerebral (or peripheral) vasodilator. Lifarizine has a monoisotopic molecular weight of 436.26 Da.
Buterizine
go.drugbank.com/drugs/DB20973ExperimentalThe usage of the INN stem '-rizine' in the name indicates that Buterizine is a antihistaminic/cerebral (or peripheral) vasodilator. Buterizine has a monoisotopic molecular weight of 466.31 Da.
Brodimoprim-4,6-Dicarboxylate
go.drugbank.com/drugs/DB02809ExperimentalThese are organic compounds contaiing a methoxybenzene or a derivative thereof. This medication is known to target the protein dihydrofolate reductase.
GDC-0425
go.drugbank.com/drugs/DB14791Investigationalinvestigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or
TT 173
go.drugbank.com/drugs/DB17717InvestigationalTT 173 is a Modified Human Tissue Factor currently being investigated to treat bleeding disorders such as hemophilia and von Willebrand disease, as well as bleeding episodes in cutaneous injuries or dental
Fluasterone
go.drugbank.com/drugs/DB06250ExperimentalHas antiproliferative effects on HIV-1 and reduces HIV-1 replication.