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Medroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalMedroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Products: Aa-medroxyHigh mobility group protein HMG-I/HMG-Y
go.drugbank.com/bio_entities/BE0012648TargetHumansHMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved...
Synonyms: High mobility group AT-hook protein 1Idarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: Aj-idarubicinZinc oxide
go.drugbank.com/drugs/DB09321ApprovedInvestigationalZinc oxide is an inorganic compound used in a number of manufacturing processes. … It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically.
Mixtures: Nars Gel Fraicheur - ST-moritz, Creal Zink Sunscreen SPF 50 Well at WalgreensCategories: Compounds used in a research, industrial, or household settingAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approved[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. … Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.
Synonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin ACategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexPropranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigationalPropranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: PROPRANOLOL AL 40, PROPRANOLOL AL 80Cisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalIt was the first member of its class, which now also includes carboplatin and oxaliplatin. … Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: OCT2 Substrates with a Narrow Therapeutic Index, Compounds used in a research, industrial, or household settingProducts: UL-PLUX, Platinol-AQLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: Protect Cardio AF, NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADETCategories: Compounds used in a research, industrial, or household settingGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalGemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233140] Gemcitabine is marketed as Gemzar and it is available as intravenous injection.
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: Aj-gemcitabine, Act Gemcitabine