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Meloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedMeloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Mixtures: NURO-B, NURO-BCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticAstrocytoma
go.drugbank.com/conditions/DBCOND0017186Drugs: CarmustineSynonyms: Astrocytoma, no ICD-O subtype, Astrocytoma, no ICD-O subtype (morphologic abnormality)Nicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalIt has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. … It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cardene Cap 30mg, Cardene IVEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalAs the binding of esomeprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists … Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme
Mixtures: RUMONAL® PRO 15, RUMONAL® PRO 7.5Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Cytochrome P-450 SubstratesUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Mixtures: Thomas Formula No 17, Thomas Formula No 47Products: U O CREAM 10%, UO CREAMAlpha-1-proteinase inhibitor
go.drugbank.com/drugs/DB00058ApprovedInvestigationalHuman alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Synonyms: 122320-05-2, Alpha-1 MPMixtures: Prolastin-CVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalSuch an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196]. … It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Eberth 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung oder zur Herstellung einer Lösung zum Einnehmen, Eberth 1000 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung oder zur Herstellung einer Lösung zum EinnehmenCongenital Plasminogen Deficiency
go.drugbank.com/conditions/DBCOND0138725Drugs: PlasminogenSynonyms: Type I Plasminogen DeficiencyUCART22
go.drugbank.com/drugs/DB17466InvestigationalUCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.
Synonyms: Allogeneic gene-edited CAR T cells UCART22, Allogeneic TALEN gene-edited CAR T-Cells UCART22MB-102 CD123 CAR
go.drugbank.com/drugs/DB17366InvestigationalMB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.