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Sparfloxacin
go.drugbank.com/drugs/DB01208ApprovedWithdrawnSparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseLysine
go.drugbank.com/drugs/DB00123ApprovedInvestigationalNutraceuticalThe ε-amino group acts as a site for hydrogen binding and a general base in catalysis. … O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSIONCategories: Detoxifying Agents for Antineoplastic TreatmentBenzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalThe quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSpinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition … to many investigations for use in other animals and agricultural plants.
Mixtures: Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 9.1-18kg, Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 18.1-27kgBedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigationalThe quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. … [A261856,A261861] It is the first drug that was approved in the last 40 years by the FDA for TB unresponsive to current treatments on the market.
Categories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisNizatidine
go.drugbank.com/drugs/DB00585ApprovedThe drug is used for the treatment of duodenal ulcers.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Voxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalPrior to Vosevi, there were no approved retreatment options for patients who have previously received, and failed, a regimen containing an NS5A inhibitor for treatment of chronic HCV infection. … Vosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, 3, 4, 5, or 6 infection [FDA Label].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseZinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: OMEGA PLUS EMULSION FOR INFUSION, OMEGA SPECIAL EMULSION FOR INFUSIONCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseLevoleucovorin
go.drugbank.com/drugs/DB11596ApprovedInvestigationalThis important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted when high-dose methotrexate is used for cancer therapy. … They are indicated for use as rescue therapy following use of high-dose methotrexate in the treatment of osteosarcoma or for diminishing the toxicity associated with inadvertent overdosage of folic acid
Categories: Detoxifying Agents for Antineoplastic TreatmentThonzylamine
go.drugbank.com/drugs/DB11235ApprovedIt is available as combination products with [DB04837] or [DB00388] for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic Use