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Displaying results 661 - 670 of 10000 in total
  1. Drug

    Imlunestrant

    go.drugbank.com/drugs/DB19043
    ApprovedInvestigational

    The FDA approved imlunestrant on September 25, 2025 [L54051] as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer with … Imlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader.

    Synonyms: (5r)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5h-(1)benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5r)-Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitors
  2. Drug

    Efinaconazole

    go.drugbank.com/drugs/DB09040
    ApprovedInvestigational

    Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis.

    Synonyms: (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanolCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Bepridil

    go.drugbank.com/drugs/DB01244
    ApprovedWithdrawn

    It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. … A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects.

    Synonyms: 1-(2-(N-BENZYLANILINO)-1-(ISOBUTOXYMETHYL)ETHYL)-PYRROLIDINE, 1-PYRROLIDENEETHANAMINE, .BETA.-((2-METHYLPROPOXY)METHYL)-N-PHENYL-N-(PHENYLMETHYL)-Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Glycolic acid

    go.drugbank.com/drugs/DB03085
    Approved

    Synonyms: 2-Hydroxyacetic acid, 2-Hydroxyethanoic acidMixtures: GLICOLIC®-H LOCION, JUVENTUS ® H LOCION
  5. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Synonyms: m-Benzoylhydratropic acid, 2-(3-Benzoylphenyl)propionic acidCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  6. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile. … Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered

    Synonyms: 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamateMixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MG
  7. Drug

    Methohexital

    go.drugbank.com/drugs/DB00474
    Approved

    An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.

    Synonyms: 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid, (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194]

    Synonyms: (±)-2-(p-isobutylphenyl)propionic acid, 2-(4-isobutylphenyl)propanoic acidInternational brands: Act-3, Alges-X
  9. Drug

    Bromfenac

    go.drugbank.com/drugs/DB00963
    ApprovedWithdrawn

    Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation.

    Synonyms: 2-amino-3-(4-bromobenzoyl)benzeneacetic acid, [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acidCategories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)
  10. Drug

    Saxagliptin

    go.drugbank.com/drugs/DB06335
    ApprovedInvestigational

    Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.

    Synonyms: (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrileMixtures: QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADET, KOMBIGLYZE ® XR 5 MG/ 1000 MG