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Rifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigationalRifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymeras...
Synonyms: 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetateCategories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersZanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigationalZanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Mantle cell lymphoma is an aggressive mature B-cell n...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesIcotrokinra
go.drugbank.com/drugs/DB21724ApprovedInvestigationalIcotrokinra is a first-in-class, targeted oral peptide and interleukin-23 (IL-23) receptor antagonist. It was jointly discovered and developed by Protagonist and Johnson & Johnson and provides a novel, oral treatment option for patie...
Phenyltoloxamine
go.drugbank.com/drugs/DB11160ApprovedPhenyltoloxamine is an antihistamine drug with sedative and analgesic effects. It is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. It is available in combination products that also contain other...
Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIsosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. Isosorbid...
Magnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigationalMagnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium in...
Mixtures: T-PA Cap, Fusion PM Formula TabProducts: MAGNEROT CLASSIC N, MAGNEROT N MAGNESIUMTABLRolapitant
go.drugbank.com/drugs/DB09291ApprovedInvestigationalBy blocking Substance P from interacting with NK-1 receptors in the gut and the central nervous system, rolapitant prevents late-phase CINV. … Neurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance P Receptor (SPR).
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesBenactyzine
go.drugbank.com/drugs/DB09023ApprovedWithdrawnBenactyzine is no longer widely used in medicine, although it is still a useful drug for scientific research. It does not possess any antihistamine properties.
Epicept NP-1
go.drugbank.com/drugs/DB05492InvestigationalEpiCept NP-1 is a prescription topical analgesic cream designed to provide effective, long-term relief from the pain of peripheral neuropathies. … EpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used antidepressant) and ketamine (an NMDA antagonist that is used as an anesthetic).
Synonyms: Epicept NP-1Sacrosidase
go.drugbank.com/drugs/DB06760ApprovedSacrosidase is a liquid enzyme preparation from S.cerevisiae used for the treatment of congenital sucrose-isomaltase deficiency (CSID). People with CSID have variable amounts of sucrose-isomaltase enzyme activity and therefore have issue...