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Formoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration … [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.
Mixtures: FLUTIFORM 125/5UG 3X120 HU, HEXALER DUOProducts: FORMOTEROLHEXALEASY 12UG/D, FORMOTEROL AL 12UG DOSISDacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalDacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma. … An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564).
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexProducts: AL QUIBAZINA®, TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLELeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigationalUnlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three … [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing downstream modulation of both gonadotropin hormone and sex steroid levels.
Products: LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE, LUCRIN DEPOT 1 AY IM/SC 3,75 MG KULLANIMA HAZIR TOZ VE COZUCU ICEREN CIFT BOLMELI ENJEKTORLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Categories: Compounds used in a research, industrial, or household settingProducts: FOLINATO DE CALCIO (EQUIVALENTE A ACIDO FOLINICO 50 MG/5ML, FOLINATO DE CALCIO 50 MGCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalUnlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. … It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
Mixtures: CANDESARTAN COMP PU 8/12.5, CANDESARTAN COMP PU 8/12.5Categories: Agents Acting on the Renin-Angiotensin SystemNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approvedNystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species. … [L10686] It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and is closely related to [amphotericin B], differing only slightly
Mixtures: OLEUM ZINC OX C NYSTAT SR, NISTATINA + OXIDO DE ZINCCategories: Compounds used in a research, industrial, or household settingCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalIt was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: CABAZITAXEL DR. REDDYSTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnTetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. … The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml.
Categories: combinations of tetracyclinesProducts: Nu-tetra Capsules 250mg, Tetracycline 3 percent a First Aid AntibioticMelperone
go.drugbank.com/drugs/DB09224InvestigationalRecently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316]. … Melperone has been used for a span of greater than 30 years in the European Union [L1316].
Categories: Dopamine D2 Receptor AntagonistsProducts: MELPERON AL 25, MELPERON AL 100Sevoflurane
go.drugbank.com/drugs/DB01236ApprovedInvestigationalVet approved[A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.[A249885] … [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient.
Products: Sevorane AF