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Methylpropylpropanediol dinitrate
go.drugbank.com/drugs/DB13408ExperimentalCategories: Vasodilators Used in Cardiac DiseasesOMS-103HP
go.drugbank.com/drugs/DB05303InvestigationalOMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
YSIL6
go.drugbank.com/drugs/DB05017ExperimentalYSIL6 is a small-molecule drug in development for the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. … The molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration.
Tanespimycin
go.drugbank.com/drugs/DB05134InvestigationalIt is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia. … Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90).
Rufloxacin
go.drugbank.com/drugs/DB13772InvestigationalRufloxacin is a quinolone antibiotic.[A31894]
Categories: Topoisomerase II InhibitorsNP2
go.drugbank.com/drugs/DB06308InvestigationalIt was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain). … NP2 is a replication defective HSV-1 based gene transfer vector engineered to express human preproenkephalin.
Distigmine
go.drugbank.com/drugs/DB13694InvestigationalIt is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. … Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.
Flortaucipir
go.drugbank.com/drugs/DB15033InvestigationalFlortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Categories: Compounds used in a research, industrial, or household settingCalcium-activated potassium channel subunit beta-4
go.drugbank.com/bio_entities/BE0004424TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium se...
Synonyms: Charybdotoxin receptor subunit beta-41-Deoxy-D-xylulose 5-phosphate
go.drugbank.com/drugs/DB02496ExperimentalThe proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate … in the non-mevalonate pathway.