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Oxantel
go.drugbank.com/drugs/DB13670InvestigationalOxantel is an anthelmintic drug that targets parasitic acetylcholine receptors.[A275093, A275098]
Categories: Antiparasitic Products, Insecticides and RepellentsSulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Categories: Sulfonamides and trimethoprim, Genito Urinary System and Sex HormonesDolastatin 10
go.drugbank.com/drugs/DB12730InvestigationalDolastatin 10 has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Liver Cancer, and Kidney Cancer, among others.
Categories: Amino Acids, Peptides, and ProteinsTheodrenaline
go.drugbank.com/drugs/DB12927InvestigationalTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Epinephrine and similars, Adrenergic and Dopaminergic AgentsAZD-4017
go.drugbank.com/drugs/DB14875InvestigationalAZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
GC-376 free acid
go.drugbank.com/drugs/DB15796ExperimentalGC-376 is a 3C-like protease (3CL<sup>pro</sup> or M<sup>pro</sup>) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … These results suggest that GC-376, and its metabolites may have therapeutic potential for Covid-19.
Categories: Amino Acids, Peptides, and ProteinsPX-478
go.drugbank.com/drugs/DB06082InvestigationalPX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha. … PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma.
D-Phenylalanine
go.drugbank.com/drugs/DB02556ExperimentalAn essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem]
Glaspimod
go.drugbank.com/drugs/DB19609ExperimentalThe usage of the INN stem '-imod' in the name indicates that Glaspimod is a immunomodulator, both stimulant/suppressive and stimulant. Glaspimod has a monoisotopic molecular weight of 1170.5 Da.
Categories: Amino Acids, Peptides, and ProteinsDomofenogene zalfaparvovec
go.drugbank.com/drugs/DB16810InvestigationalDomofenogene zalfaparvovec, formerly known as BMN-307, is an investigational AAV5-phenylalanine hydroxylase (PAH) gene therapy developed by BioMarin Pharmaceutical.