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Displaying results 6761 - 6770 of 10000 in total
  1. Drug

    Verteporfin

    go.drugbank.com/drugs/DB00460
    ApprovedInvestigational

    Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and [CL-315585]. … It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration.

    Categories: Heterocyclic Compounds with 4 or More Rings, Heterocyclic Compounds, 1-RingProducts: VISUDYNE INFÜZYON SOLÜSYONU İÇİN TOZ, 1 ADET, VISUDYNE FOR INJECTION 15 mg/vial
  2. Drug

    Regorafenib

    go.drugbank.com/drugs/DB08896
    ApprovedInvestigational

    FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET, STIVARGA 40 MG TABLETA RECUBIERTA
  3. Drug

    Fenspiride

    go.drugbank.com/drugs/DB08979
    Investigational

    Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.

    Products: OXOFEN 2 MG/ML ŞURUP ,150 ML, PASFEN 2MG/ML ŞURUP
  4. Drug

    Octocrylene

    go.drugbank.com/drugs/DB09535
    Approved

    Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure.

    Mixtures: Eco Soul Bounce Crea m Foundation 02 Natural Beige, Me Day T3 SPF 25Products: Panama Jack SPF 4, Panama Jack SPF 4 Dark Tanning Oil
  5. Drug

    Belatacept

    go.drugbank.com/drugs/DB06681
    ApprovedInvestigational

    Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. … Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human

    Categories: Selective T Cell Costimulation Blocker, T Lymphocyte Costimulation Activity BlockadeProducts: NULOJIX ®250 MG/ VIAL POLVO LIOFILIZADO PARA SOLUCION INYECTABLE INTRAVENOSA
  6. Drug

    Aluminum oxide

    go.drugbank.com/drugs/DB11342
    ApprovedWithdrawn

    Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications.

    Mixtures: POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSProducts: ALUTACID ANTACID MIXTURE 4% w/w, ALUMINIUM HYDROXIDE MIXTURE BP 4% w/w
  7. Drug

    Tetrofosmin

    go.drugbank.com/drugs/DB11180
    Approved

    It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. … Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788]

    Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelCategories: P-glycoprotein substrates
  8. Target

    Nectin-4

    go.drugbank.com/bio_entities/BE0009798
    TargetHumans

    Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells

    Polypeptides: Nectin-4Synonyms: Nectin cell adhesion molecule 4, Poliovirus receptor-related protein 4
  9. Target

    Phosphodiesterase 4

    go.drugbank.com/bio_entities/BE0011004
    TargetHumans

    Hydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes

    Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4A, 3',5'-cyclic-AMP phosphodiesterase 4BFunction: 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-AMP phosphodiesterase activity
  10. Drug

    Benzalkonium

    go.drugbank.com/drugs/DB11105
    ApprovedInvestigational

    Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. … This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal drops or sprays as an excipient ingredient serving as an antimicrobial preservative [FDA Label]

    Mixtures: WIPE OUT 3 PACK 2 Lemon Scent 1 Fresh Scent, WIPE OUT 3 PACK 2 Lemon Scent 1 Fresh ScentCategories: Compounds used in a research, industrial, or household setting