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ABX1100
go.drugbank.com/drugs/DB17655InvestigationalABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle. … It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.[L45978]
Utatrectinib
go.drugbank.com/drugs/DB21295InvestigationalThe usage of the INN stem '-trectinib' in the name indicates that Utatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.
CR665
go.drugbank.com/drugs/DB05155ExperimentalCR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. … In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound.
Vincamine
go.drugbank.com/drugs/DB13374InvestigationalVincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Mozafancogene autotemcel
go.drugbank.com/drugs/DB17723InvestigationalRP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
V116517
go.drugbank.com/drugs/DB16060InvestigationalV116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
Iodipamide
go.drugbank.com/drugs/DB04711ApprovedWithdrawnIodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Talactoferrin alfa
go.drugbank.com/drugs/DB05426InvestigationalIt increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation.
Elbimilast
go.drugbank.com/drugs/DB20663InvestigationalThe usage of the INN stem '-milast' in the name indicates that Elbimilast is a Phosphodiesterase-4 (PDE4) inhibitor.