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Icenticaftor
go.drugbank.com/drugs/DB21466InvestigationalThe usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier. … Icenticaftor is a small molecule drug.
Linvencorvir
go.drugbank.com/drugs/DB21544InvestigationalLinvencorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. … Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).
Fipravirimat
go.drugbank.com/drugs/DB21578InvestigationalFipravirimat is a small molecule drug. The usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation. … Fipravirimat is under investigation in clinical trial NCT04493216 (A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults).
Foselutoclax
go.drugbank.com/drugs/DB21663InvestigationalFoselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax is under investigation in clinical trial NCT06011798 (Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)).
Gluconolactone
go.drugbank.com/drugs/DB04564ApprovedGluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. … Pure gluconolactone is a white odorless crystalline powder.
Furazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approvedA nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimineFT516
go.drugbank.com/drugs/DB15732InvestigationalFT516 is currently being tested against acute myeloid leukemia, B-cell lymphoma, and solid tumors in combination with other compounds. It is also a potential therapy for COVID-19. … This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.
Afacifenacin
go.drugbank.com/drugs/DB21385ExperimentalAfacifenacin is a small molecule drug. The usage of the INN stem '-fenacin' in the name indicates that Afacifenacin is a muscarinic receptor antagonist. … Afacifenacin has a monoisotopic molecular weight of 481.2 Da.
Fosifidancitinib
go.drugbank.com/drugs/DB21462ExperimentalFosifidancitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Fosifidancitinib is a Janus kinase inhibitor. … Fosifidancitinib has a monoisotopic molecular weight of 505.12 Da.