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Displaying results 6781 - 6790 of 10000 in total
  1. Drug

    Balixafortide

    go.drugbank.com/drugs/DB15370
    Investigational

    Balixafortide is under investigation in clinical trial NCT03786094 (Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer).

  2. Drug

    Ladiratuzumab vedotin

    go.drugbank.com/drugs/DB15409
    Investigational

    Ladiratuzumab vedotin is under investigation in clinical trial NCT01969643 (A Safety Study of SGN-LIV1A in Breast Cancer Patients).

  3. Drug

    Volenrelaxin

    go.drugbank.com/drugs/DB21750
    Investigational

    Volenrelaxin is under investigation in clinical trial NCT06598631 (Efficacy and Safety of Volenrelaxin in Adults With Chronic Kidney Disease).

  4. Drug

    Edaxeterkib

    go.drugbank.com/drugs/DB21490
    Investigational

    Edaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da. … The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor.

  5. Drug

    Eptifibatide

    go.drugbank.com/drugs/DB00063
    ApprovedInvestigational

    Synthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide th...

  6. Drug

    Nomacopan

    go.drugbank.com/drugs/DB14991
    Investigational

    Nomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).

  7. Drug

    Isuzinaxib

    go.drugbank.com/drugs/DB19109
    Investigational

    Isuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).

  8. Drug

    Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16714
    ApprovedInvestigational

    The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

  9. Drug

    Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16717
    ApprovedInvestigational

    The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

  10. Drug

    Mesterolone

    go.drugbank.com/drugs/DB13587
    Investigational

    Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH [A27177, A27178]. … It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen.