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Pebezertinib
go.drugbank.com/drugs/DB21705InvestigationalThe usage of the INN stem '-ertinib' in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Inlexisertib
go.drugbank.com/drugs/DB21713InvestigationalThe usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor.
FRAX597
go.drugbank.com/drugs/DB31734ExperimentalFRAX597 is a small molecule drug that inhibits the p21-activated kinases (PAKs).[A274673, A274678]
Ozekibart
go.drugbank.com/drugs/DB18675InvestigationalOzekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Synonyms: Tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5).Opiranserin
go.drugbank.com/drugs/DB16271InvestigationalOpiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).
AG-858
go.drugbank.com/drugs/DB05502InvestigationalTumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models.
Alofanib
go.drugbank.com/drugs/DB20918InvestigationalThe usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor.
ND1251
go.drugbank.com/drugs/DB05132ExperimentalND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression.