Search

Displaying results 671 - 680 of 10000 in total
  1. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after

    Mixtures: SR Tablet 50/200, CARBIDOPA X 25 MG Y LEVODOPA X 250 MGSynonyms: 3-Hydroxy-L-tyrosine, (−)-3-(3,4-dihydroxyphenyl)-L-alanine
  2. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. … Once in its activated form, APC functions as a serine protease with potent anticoagulant effects, especially in the presence of its cofactor protein S.

    Mixtures: Beriplex P/n 500, Beriplex P/n 1000Categories: protein C
  3. Drug

    CX-717

    go.drugbank.com/drugs/DB05047
    IllicitInvestigational

    CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    CRx-401

    go.drugbank.com/drugs/DB05775
    Experimental

    CRx-401 is a novel insulin sensitizer designed to provide anti-diabetic activity without promoting weight gain. … In third-party clinical studies, the dose of bezafibrate contained in CRx-401 has been observed to have a positive impact on cellular pathways that influence glycemic and lipid profiles, and this dose

  5. Drug

    Selenomethionine Se-75

    go.drugbank.com/drugs/DB09400
    Approved

    Mixtures: Megavite RxSynonyms: Selenomethionine (75 Se), Selenomethionine Se 75
  6. Drug

    Mifepristone

    go.drugbank.com/drugs/DB00834
    ApprovedInvestigational

    Mifepristone is a progestational and glucocorticoid hormone antagonist. … The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression (phase 3 trials).

    Mixtures: Mpm Pak, Mpm PakCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  7. Drug

    Menthyl salicylate

    go.drugbank.com/drugs/DB11201
    Approved

    Menthyl salicylate is an ester of menthol and salicylic acid [L2808]. This product is used to treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains) [L2810].

    Mixtures: Rx Act, Ds Super 7 Pain ReliefSynonyms: 1-Menthyl salicylate
  8. Drug

    Dyphylline

    go.drugbank.com/drugs/DB00651
    ApprovedWithdrawn

    Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

    Mixtures: Jay-Phyl, Dy GCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Kappadione

    go.drugbank.com/drugs/DB09332
    Approved

    Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is … Studies involving the active metabolite of this formulation, menadione, showed oocyte toxicity in a study of mice [L1544].

  10. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.

    Mixtures: DermacinRx DPN PakCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates