This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Selenomethionine Se-75
- DrugBank Accession Number
- DB09400
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Selenomethionine Se-75 (DB09400)
- Weight
- Average: 192.071
Monoisotopic: 192.001502169 - Chemical Formula
- C5H11NO2Se
- Synonyms
- Selenomethionine (75 Se)
- Selenomethionine (75Se)
- Selenomethionine Se 75
- Selenometionina (75 Se)
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareEltrombopag The bioavailability of Selenomethionine Se-75 can be decreased when combined with Eltrombopag. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Selenium unknown H6241UJ22B 7782-49-2 BUGBHKTXTAQXES-UHFFFAOYSA-N - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Megavite Rx Selenomethionine Se-75 (50 ug/1) + Ascorbic acid (500 mg/1) + Biotin (150 ug/1) + Chromic chloride hexahydrate (0.1 mg/1) + Cupric oxide (3 mg/1) + Cyanocobalamin (50 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Ferrous fumarate (27 mg/1) + Folic acid (1 mg/1) + Lemon (50 mg/1) + Magnesium oxide (50 mg/1) + Manganese (5 mg/1) + Nicotinamide (100 mg/1) + Calcium pantothenate (25 mg/1) + Pyridoxine hydrochloride (25 mg/1) + Riboflavin (20 mg/1) + Thiamine mononitrate (20 mg/1) + Vitamin A acetate (2000 [iU]/1) + Zinc oxide (22.5 mg/1) Tablet, film coated Oral Breckenridge Pharmaceutical, Inc. 2009-06-01 2010-03-31 US 
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Carboxylic acids and derivatives
- Sub Class
- Amino acids, peptides, and analogues
- Direct Parent
- L-alpha-amino acids
- Alternative Parents
- Fatty acids and conjugates / Amino acids / Selenoethers / Monocarboxylic acids and derivatives / Carboxylic acids / Organopnictogen compounds / Organic oxides / Monoalkylamines / Hydrocarbon derivatives / Carbonyl compounds
- Substituents
- Aliphatic acyclic compound / Amine / Amino acid / Carbonyl group / Carboxylic acid / Fatty acid / Hydrocarbon derivative / L-alpha-amino acid / Monocarboxylic acid or derivatives / Organic nitrogen compound
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- P6708E7555
- CAS number
- 1187-56-0
- InChI Key
- RJFAYQIBOAGBLC-ZEMBQCNESA-N
- InChI
- InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i9-4
- IUPAC Name
- (2S)-2-amino-4-[methyl(⁷⁵Se)selanyl]butanoic acid
- SMILES
- C[75Se]CC[C@H](N)C(O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 59637
- 9133
- ChEMBL
- CHEMBL1201054
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, film coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 109.0 mg/mL ALOGPS logP -2.5 ALOGPS logP -3.3 Chemaxon logS -0.25 ALOGPS pKa (Strongest Acidic) 1.56 Chemaxon pKa (Strongest Basic) 9.5 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 63.32 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 42.91 m3·mol-1 Chemaxon Polarizability 14.64 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 123.64188 predictedDeepCCS 1.0 (2019) [M+H]+ 127.33567 predictedDeepCCS 1.0 (2019) [M+Na]+ 136.4233 predictedDeepCCS 1.0 (2019)
Drug created at November 30, 2015 19:10 / Updated at June 01, 2022 17:06