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Ethambutol
go.drugbank.com/drugs/DB00330ApprovedInvestigational[A229048] Ethambutol was granted FDA approval on 6 November 1967.[L31663] … [L31743] Ethambutol was first described in the literature in 1961.[A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.
Synonyms: (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamineProducts: Myambutol Tab 100mg, E-BUTOL TABLET 400 mgZinc
go.drugbank.com/drugs/DB01593ApprovedInvestigationalIt is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. … zinc in diabetes [A32416].
Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Tar-endSynonyms: ZnVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceProducts: CHAMPIX 1.0MG FILM-COATED TABLETSCyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalIt is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females. … An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties.
Mixtures: ESTELLE-35 ED TABLET, LADY-TEN 35 COMPRIMIDOS RECUBIERTOSProducts: CYPROTERON TAD 100MG TABLSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnSibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Products: SIBESY(R)10MG CAPSULAS, CONTROLEX 10MG CAPSULASFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: Supravite Stress Avec Vit E Et Fer, Ribotin-EProducts: FEFUR TABLET (FILM-COATED) 100MG, Novo-fumar 200mgNimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalIt acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Compared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation.
Products: ORBEREC® 10MG/50ML SOLUCIÓN INYECTABLE, NIMODIPINA EGVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalrole in the efficacy of SRIs in treating depression. … agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors.
Products: KELAC® 10MG, BRINTELLIX FILM-COATED TABLETS 10MGFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.
Products: Fluvastatin Sodium ER, FLUVASTATINA EGPrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Products: PREDNISON 10MG GALEN, PREDNISONE EG