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AZD0947
go.drugbank.com/drugs/DB04848ExperimentalAs of March 2003, the drug was in phase II trials; however, as of October 2004, it no longer appeared on the company’s development pipeline. … AZD0947 is a K+ channel opener, which was under investigation by AstraZeneca for the treatment of overactive bladder.
Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalBecause of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals. … An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography.
Olinciguat
go.drugbank.com/drugs/DB15238Investigational, Olinciguat (IW-1701), in Healthy Volunteers). … Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator
Mangostin
go.drugbank.com/drugs/DB14371InvestigationalMangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Pumice
go.drugbank.com/drugs/DB14374InvestigationalPumice is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineTefidsogene civaparvovec
go.drugbank.com/drugs/DB16789InvestigationalDeveloped by Sangamo Therapeutics, tefidsogene civaparvovec is being investigated in mucopolysaccharidosis type II.[A258789, L45949] … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes
Allogeneic Cardiosphere-Derived Cells
go.drugbank.com/drugs/DB15744InvestigationalTNFa, IFN-y, IL-1B, and IL-15). The anti-inflammatory effects of CDC work through polarizing macrophages and restoring tissue function.