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Methylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalMethylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Afr...
Synonyms: Basic Blue 9, C.I. basic blue 9Mixtures: Urin D/S, Uretron D/SEluxadoline
go.drugbank.com/drugs/DB09272ApprovedInvestigationalEluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … reduced colonic motility, while antagonism of central delta-opioid receptors results in improved analgesia, making eluxadoline usable for the symptoms of both pain and diarrhea characteristic of IBS-D.
Synonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acidCategories: Heterocyclic Compounds, 1-RingTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and prevent HIV-1 infections. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.
Mixtures: GENVOYA ® TABLETAS RECUBIERTAS, DESCOVY® 200MG/10MG TABLETAS RECUBIERTASCategories: Vitamin B Complex, Cytochrome P-450 SubstratesButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedButylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Synonyms: N-butylscopolammonium, N-butylscopolammonium ionMixtures: GENO DOL®, DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLESetiptiline
go.drugbank.com/drugs/DB09304ExperimentalSetiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
Categories: Heterocyclic Compounds, 3-RingAlatrofloxacin
go.drugbank.com/drugs/DB09335ApprovedWithdrawnAlatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingPropoxycaine
go.drugbank.com/drugs/DB09342ApprovedPropoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride [L1588].
Metrizoic acid
go.drugbank.com/drugs/DB09346ApprovedMetrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. … A total of 10, 000 injections were administered to 2,028 patients undergoing angiocardiographic procedures over a three-year period.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedLevobetaxolol
go.drugbank.com/drugs/DB09351ApprovedLevobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma. … It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon but has been discontinued.
Synonyms: (S)-betaxololCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesFluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalSodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. … It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection.
Synonyms: Fluoride ion F-18Salts: Sodium fluoride F-18