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Tramazoline
go.drugbank.com/drugs/DB13064InvestigationalTramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).
Malonyl-CoA
go.drugbank.com/drugs/DB04524ExperimentalA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
go.drugbank.com/drugs/DB01774ExperimentalServes as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]
Aminooxyacetic acid
go.drugbank.com/drugs/DB02079ExperimentalA compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
nor-NOHA
go.drugbank.com/drugs/DB02381InvestigationalN-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).
Synonyms: N-hydroxy-nor-arginine, N-hydroxy-nor-L-argininePF-04856884
go.drugbank.com/drugs/DB17550Investigational[A257291] It is under investigation in clinical trial NCT01441414 (PF-04856884 (CVX-060) in Combination With Axitinib in Patients With Previously Treated Metastatic Renal Cell Carcinoma).
Inlexisertib
go.drugbank.com/drugs/DB21713InvestigationalInlexisertib is under investigation in clinical trial NCT05957367 (A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies). … The usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor.
Basic Fibroblast Growth Factor
go.drugbank.com/drugs/DB14131InvestigationalThe growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. … Although it is not approved for use in Canada or the USA, bFGF is currently undergoing investigation in a number of clinical trials.
Efzofitimod
go.drugbank.com/drugs/DB16453InvestigationalIt is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
COVID-19 convalescent plasma
go.drugbank.com/drugs/DB15692Investigational), and use for single patients through an emergency IND (eIND; 21 CFR 312.310). … [L14333] This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR 312.305