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Displaying results 6821 - 6830 of 10000 in total
  1. Drug

    Beta carotene

    go.drugbank.com/drugs/DB06755
    ApprovedNutraceutical

    [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed of two retinyl groups. … [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).[L2191]

    Mixtures: ACECAP 20/200/200 MG YUMUŞAK KAPSÜL, 30 ADET, Folika-MGCategories: Vitamin A
  2. Drug

    Sulodexide

    go.drugbank.com/drugs/DB06271
    ApprovedInvestigationalWithdrawn

    Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

    Products: ANJIOFLUX 600 LRU 2 ML ENJEKTABL COZELTI ICEREN 10 AMPUL, VESSEL DUE F
  3. Drug

    Efalizumab

    go.drugbank.com/drugs/DB00095
    ApprovedWithdrawn

    Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. … It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]

    Products: RAPTIVA ®125 MG
  4. Drug

    Metyrapone

    go.drugbank.com/drugs/DB01011
    ApprovedInvestigational

    It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.

    Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InducersProducts: Metycor 250 mg Weichkapseln
  5. Drug

    Nystatin

    go.drugbank.com/drugs/DB00646
    ApprovedInvestigationalVet approved

    [A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate … Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.

    Mixtures: NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 6 ADET, NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 12 ADETCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Zanubrutinib

    go.drugbank.com/drugs/DB15035
    ApprovedInvestigational

    L10166] which measures the proportion of patients in a trial whose tumour is entirely or partially destroyed by a drug. … [A187967] BTK is an enzyme that plays a role in oncogenic signalling pathways, promoting the survival and proliferation of malignant B cells.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: BRUKINSA 80 mg capsules
  7. Drug

    Tauroursodeoxycholic acid

    go.drugbank.com/drugs/DB08834
    ApprovedInvestigationalWithdrawn

    Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.

    Products: TAUROLITE 250 MG 100 KAPSUL
  8. Drug

    Iocetamic acid

    go.drugbank.com/drugs/DB09403
    Approved

    Iocetamic acid is a diagnostic aid (radiopaque medium)

    Categories: X-Ray Contrast Media, Iodinated, Watersoluble, Hepatotropic X-Ray Contrast MediaProducts: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)
  9. Drug

    Telithromycin

    go.drugbank.com/drugs/DB00976
    Approved

    Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: KETEK ® 400 MG
  10. Target

    Solute carrier family 2, facilitated glucose transporter member 4

    go.drugbank.com/bio_entities/BE0000893
    TransporterTargetHumans

    Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained ...

    Polypeptides: Solute carrier family 2, facilitated glucose transporter member 4Synonyms: GLUT-4, Glucose transporter type 4, insulin-responsive