Solute carrier family 2, facilitated glucose transporter member 4

BE0000893ProteinHumansSLC2A4

Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. It is acted on by 10 drugs in DrugBank.

Gene name
SLC2A4
UniProtKB entry
P14672Swiss-Prot
Cellular location
Cell membrane
Residues / weight
509 residues · 54,787 Da
Also known as
Glucose transporter type 4, insulin-responsive · GLUT-4 · GLUT4

Resolves to

Protein
UniProtP14672UniProt nameGLUT4_HUMAN
Gene
HGNCHGNC:11009NCBI Gene6517GenBank307076GeneCardsSLC2A4
Pharmacology
KEGGhsa:6517
Structure
PDB7WSMPDB7WSN
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 2, facilitated glucose transporter member 4, how selective are they, and which programs against it are still in active trials?

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