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MORF-057
go.drugbank.com/drugs/DB23674InvestigationalMORF-057 is under investigation in clinical trial NCT06226883 (A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease).
rhIGFBP-3
go.drugbank.com/drugs/DB05897InvestigationalIt is developed by Insmed and is currently under phase I of the clinical trial.
OBE101
go.drugbank.com/drugs/DB05080ExperimentalIt is a new formulation that is based on the vertigo medication, Betahistine. … Obecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment of obese individuals and for other weight management indications.
Leukotriene C4
go.drugbank.com/drugs/DB08855ExperimentalThe conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. … It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycineZavacorilant
go.drugbank.com/drugs/DB21509InvestigationalThe usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).
Neladalkib
go.drugbank.com/drugs/DB21712InvestigationalThe usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor.
Fenspiride
go.drugbank.com/drugs/DB08979InvestigationalIt is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis … Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.
Xiliertinib
go.drugbank.com/drugs/DB21453InvestigationalThe usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor.
Paltimatrectinib
go.drugbank.com/drugs/DB21588InvestigationalThe usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.
Interferon Kappa
go.drugbank.com/drugs/DB15749ExperimentalInterferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and