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AG0301-COVID19
go.drugbank.com/drugs/DB15856InvestigationalThe candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting the SARS-CoV-2 spike protein. … The gene transfer method increases the efficiency of gene expression and antibody production capability, garnering a more efficient DNA vaccine product.
Mivebresib
go.drugbank.com/drugs/DB21300InvestigationalThe usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.
Interferon Kappa
go.drugbank.com/drugs/DB15749ExperimentalInterferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and
Cambinol
go.drugbank.com/drugs/DB15493ExperimentalCambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival under stress. This activity is currently being investigated for its use as a cancer treatment.
EVT 302
go.drugbank.com/drugs/DB06057InvestigationalIt is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.
Captodiame
go.drugbank.com/drugs/DB09014ExperimentalCaptodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
BI-K0376
go.drugbank.com/drugs/DB05858ExperimentalIt is under investigation by Pfizer and has gone through phase I of the clinical trails.
Nanrilkefusp alfa
go.drugbank.com/drugs/DB17480InvestigationalNanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).
BEA-17
go.drugbank.com/drugs/DB18574ExperimentalBEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST.[L48330] It is under investigation for the treatment of glioblastoma.
Rhein
go.drugbank.com/drugs/DB13174ExperimentalIt is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.