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Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
go.drugbank.com/bio_entities/BE0002004TargetEscherichia coli (strain K12)Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
Polypeptides: Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitiveSynonyms: Phospho-2-keto-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthaseActin-related protein 2/3 complex subunit 5
go.drugbank.com/bio_entities/BE0004255TargetHumansThe Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). … Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 5Synonyms: Arp2/3 complex 16 kDa subunitGemtuzumab ozogamicin
go.drugbank.com/drugs/DB00056ApprovedInvestigationalGemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. … It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who have experienced a relapse or who have not responded to initial treatment (refractory) [L941].
Products: MYLOTARG 5 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 FLAKON, MYLOTARG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 5MG/VIALBrodalumab
go.drugbank.com/drugs/DB11776ApprovedInvestigationalBrodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-sever...
Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A AntagonistsProducts: LUMICEF SUBCUTANEOUS INJECTION 210 MG SYRINGEDimercaptosuccinic acid
go.drugbank.com/drugs/DB14089ApprovedInvestigationalCategories: Compounds used in a research, industrial, or household settingProducts: MON.DMSA KIT 1 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADETLynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of [norethisterone].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADETCalcium Phosphate
go.drugbank.com/drugs/DB11348ApprovedInvestigationalCalcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Mixtures: MULTIVIT M® CAPSULAS, Stom #2Categories: ascorbic acid (vit C) and calcium, Compounds used in a research, industrial, or household settingGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigational[A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other therapies. … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.
Categories: fms-Like Tyrosine Kinase 3, antagonists & inhibitors, MATE 1 InhibitorsProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET, XOSPATA® FILM-COATED TABLETS 40MGAsunaprevir
go.drugbank.com/drugs/DB11586ApprovedWithdrawnAsunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. … It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsProducts: SUNVEPRA® 100MG CÁPSULAS BLANDAS, SUNVEPRA 100 MG KAPSÜL, 56 ADETMebrofenin
go.drugbank.com/drugs/DB15779ApprovedProducts: POLTECHMBRIDA 20 MG. KIT PARA LA PREPARACION RADIOFARMACEUTICA