Actin-related protein 2/3 complex subunit 5

BE0004255ProteinHumansARPC5

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). It is acted on by 2 drugs in DrugBank.

Gene name
ARPC5
UniProtKB entry
O15511Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
151 residues · 16,320 Da
Also known as
ARC16 · Arp2/3 complex 16 kDa subunit · p16-ARC

Resolves to

Protein
UniProtO15511UniProt nameARPC5_HUMAN
Gene
HGNCHGNC:708NCBI Gene10092GenBank2282042GeneCardsARPC5
Pharmacology
KEGGhsa:10092
Structure
PDB6UHCPDB6YW7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Actin-related protein 2/3 complex subunit 5, and which indications are they being tested in?

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