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Displaying results 681 - 690 of 6949 in total
  1. Drug

    Domvanalimab

    go.drugbank.com/drugs/DB18848
    Investigational

    Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).

    Synonyms: Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa
  2. Drug

    Seladelpar

    go.drugbank.com/drugs/DB12390
    ApprovedInvestigational

    [L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a condition associated with aberrant bile acid metabolism … Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. Seladelpar is a single enantiomer of the R-configuration.

    Synonyms: (4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)SULFANYL)-2-METHYLPHENOXY)ACETIC ACID PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) AGONIST,ANTIHYPERLIPIDAEMIC
  3. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent n...

    Mixtures: Se-Tan PLUS, For-2Products: Derma Pella Facial Cleanser for Normal Skin, Derma Pella Cleanser for Sensitive and Dry Skin
  4. Drug

    NKX101

    go.drugbank.com/drugs/DB18131
    Investigational

    NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.

    Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15
  5. Drug

    Enapotamab vedotin

    go.drugbank.com/drugs/DB16156
    Investigational

    Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).

    Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotin
  6. Drug

    Sodium fluorophosphate

    go.drugbank.com/drugs/DB09484
    ApprovedInvestigational

    Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

    Mixtures: Topol Plus Whitening Tpt for Sensitive Teeth, Rembrandt Whitening Toothpaste for Sensitive TeethProducts: Far Infra Silver, Need For You Limpio Tooth
  7. Drug

    EB05

    go.drugbank.com/drugs/DB16477
    Investigational

    EB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.

    Synonyms: Immunoglobulin G1 [326-serine,329-phenylalanine,de-448-lysine], anti-(human Toll-like receptor 4) (human-Mus musculus monoclonal EB05 γ1-chain), disulfide with human-Mus musculus monoclonal EB05 κ-chainCategories: Experimental Unapproved Treatments for COVID-19
  8. Drug

    Alanyl glutamine

    go.drugbank.com/drugs/DB11876
    Investigational

    Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).

    Products: Kipo for IV Infusion 200 mg/ml
  9. Drug

    Zilovertamab

    go.drugbank.com/drugs/DB18403
    Investigational

    Synonyms: Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa.-chain, dimer
  10. Drug

    Sabatolimab

    go.drugbank.com/drugs/DB16322
    Investigational

    Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).

    Synonyms: Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculus, Immunoglobulin g4-kappa, anti-(homo sapiens havcr2 (hepatitis a virus cellular receptor 2, t-cell immunoglobulin mucin family member 3, tim-3, tim3, timd3, cd366)), humanized monoclonal antibody