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Aminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Categories: Photosensitizing Agents for PhototherapySynonyms: 5-ALA, δ-ALAAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigationalAnti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified … [A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a key role for the alternative complement pathway and, in particular, the interaction between the anaphylatoxin
Categories: Complement 5a Receptor AntagonistLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines.
Synonyms: L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid, 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acidCategories: Compounds used in a research, industrial, or household setting, Detoxifying Agents for Antineoplastic Treatmentalpha-Linolenic acid
go.drugbank.com/drugs/DB00132ApprovedInvestigationalNutraceuticalWithdrawnAlpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Mixtures: Bio-efa Borage Gla 90 CapSynonyms: ALAOmbitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalgenotype 1a without cirrhosis or with compensated cirrhosis. … First approved in January 2015, Holkira Pak is indicated for the treatment of HCV genotype 1b with or without cirrhosis, and when combined with [DB00811] for the treatment of HCV genotype 1a with or without
Categories: Antivirals for Systemic Use, Treatments for Hepatitis CNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA). … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]
Synonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineCategories: Antidepressive Agents Indicated for Depression, P-glycoprotein substrates with a Narrow Therapeutic IndexSpinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. … Spinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition
Mixtures: Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 9.1-18kg, Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 18.1-27kgCategories: Compounds used in a research, industrial, or household settingNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … of illnesses caused by other protozoa or helminths [A31976].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORALMoxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approved[A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June 13, 2018.[L2970] … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side chain at carbon 25 and a unique methoxime moiety at carbon 23.
Mixtures: Advocate Spot-on Solution for Small Dogs, Advocate Spot-on Solution for Large DogsCategories: Compounds used in a research, industrial, or household settingMetacycline
go.drugbank.com/drugs/DB00931ApprovedA broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use