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Enalaprilat
go.drugbank.com/drugs/DB09477ApprovedInvestigationalEnalaprilat was originally created to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and left a metallic taste in the mouth. … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume
Categories: Agents Acting on the Renin-Angiotensin SystemProducts: Vasotec IVParicalcitol
go.drugbank.com/drugs/DB00910ApprovedInvestigationalParicalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. … Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Products: PARICAVER 5 MCG/1 ML IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, PARICAVER 10 MCG/2 ML IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPULTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). … In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Synonyms: N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamideProducts: EMEDUR 200 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 50 ADET, EMEDUR 200 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 100 ADETInterferon alfa-n1
go.drugbank.com/drugs/DB00011ApprovedWithdrawnInterferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.
Categories: Interferon Type ISynonyms: Interferon alpha-n1 (INS)Busulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalBusulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: IV BUSULFEX INJECTION, BUSULTU 6 MG/ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ, 1 ADETPotassium gluconate
go.drugbank.com/drugs/DB13620ApprovedIt is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining cell function [A32222]. … Potassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. It is also used as a potassium supplement [L2657]. Potassium is an essential nutrient.
Mixtures: Cal-mag Plus K, Mn and Zn CapletsProducts: ION-K SOLUCIÓN ORAL 31.2%(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
go.drugbank.com/drugs/DB07124ExperimentalSynonyms: (2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINEThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnIt is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. … A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: Pentothal Inj 25mg/ml, Pentothal Inj 500mg/syrTrastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: KADCYLA 100 MG IV INFUZYONLUK COZELTI KONSANTRESI ICIN TOZ, KADCYLA 160 MG IV INFUZYONLUK COZELTI KONSANTRESI ICIN TOZNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnNonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household settingProducts: Gynol II Extra Strength