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Displaying results 681 - 690 of 10000 in total
  1. Drug

    Olezarsen

    go.drugbank.com/drugs/DB18728
    ApprovedInvestigational

    Olezarsen is an antisense oligonucleotide that targets the messenger RNA (mRNA) for apolipoprotein C-III (APOC3, apoC-III),[L52033] which is a key regulator of triglyceride levels in plasma, in the liver … [A264888,A264893] Olezarsen is conjugated to a ligand containing three N-acetyl-galactosamine (GalNAc) residues to enable its delivery to hepatocytes.

    Synonyms: DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL), ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.
  2. Drug

    Ripertamab

    go.drugbank.com/drugs/DB16314
    Investigational

    Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens ms4a1 (membrane-spanning 4-domains subfamily a member 1, cd20)), chimeric monoclonal antibody, Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma.1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa.-chain, dimer
  3. Drug

    Nalotimagene carmaleucel

    go.drugbank.com/drugs/DB19155
    Investigational

    Synonyms: Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from Mo, human culture expanded activated allogeneic T cells for adjunctive immunotherapy.
  4. Drug

    Fimaporfin

    go.drugbank.com/drugs/DB17253
    Investigational

    Synonyms: 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid, mixture of three isomers a, b and c (25%, 50%, 25%)
  5. Drug

    Izokibep

    go.drugbank.com/drugs/DB19081
    Investigational

    Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).

    Synonyms: FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING
  6. Drug

    Copper oxodotreotide Cu-64

    go.drugbank.com/drugs/DB15873
    Approved

    [A220348] Further studies should be performed to compare the two tracers. … [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution.

    Synonyms: Copper 64-DOTA-tate, Copper Cu-64 dotatateCategories: Copper Radioisotopes
  7. Drug

    Fosbretabulin

    go.drugbank.com/drugs/DB12577
    Investigational

    Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.

    Synonyms: Combretastatin A-4 phosphate, Combretastatin A4 phosphate
  8. Drug

    Copper histidinate

    go.drugbank.com/drugs/DB32041
    Approved

    Menkes disease is a rare, X-linked recessive disorder caused by pathogenic variants in the ATP7A gene, which encodes a copper transport protein essential for absorbing dietary copper and transporting it … [A275383] Copper histidinate is a subcutaneously-administered copper-histidine complex that allows for copper supplementation in patients with defective ATP7A transporters.

    Synonyms: Copper histidine, Copper histidinate
  9. Drug

    Copper gluconate

    go.drugbank.com/drugs/DB11246
    ApprovedInvestigational

    Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. … According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005

    Synonyms: Copper gluconateMixtures: Vitamin A C E W.niacinam.beta Car.and Min., SENSITRACE®
  10. Drug

    Cupric sulfate

    go.drugbank.com/drugs/DB06778
    Approved

    Some of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent in analytic chemistry, as an electrolyte for batteries and electroplating baths, and in medical … The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary source [A32221].

    Synonyms: Copper sulfate (1:1), Copper(2+) sulfateInternational brands: M-Care, Hi Trace Copper