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Displaying results 681 - 690 of 8171 in total
  1. Drug

    Pibrentasvir

    go.drugbank.com/drugs/DB13878
    ApprovedInvestigational

    Mavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with regimens either containing an NS5A inhibitor or an NS3/4A protease inhibitor, but not both [L940]. … Pibrentasvir is available as an oral combination therapy with [DB13879] under the brand name Mavyret.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    Antipyrine

    go.drugbank.com/drugs/DB01435
    Approved

    An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  3. Drug

    Bismuth subnitrate

    go.drugbank.com/drugs/DB13209
    ApprovedWithdrawn

    The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.

  4. Drug

    Human thrombin

    go.drugbank.com/drugs/DB11571
    ApprovedInvestigational

    Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting.

    Mixtures: EVICEL® SELLANTE DE FIBRINA HUMANA, EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml
  5. Drug

    Choline salicylate

    go.drugbank.com/drugs/DB14006
    ApprovedNutraceutical

    The UK government has regulated its use, due to toxicity in those under 16 years of age. … This medicine can also be used for fever [L2129]. Choline Salicylate is the choline salt of salicylic acid, used as an analgesic, antipyretic and antirheumatic.

    Mixtures: Vanapain PM, Texaclear PM Pain Reliever Sleep Aid
  6. Drug

    Thrombin

    go.drugbank.com/drugs/DB11300
    ApprovedInvestigational

    Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which...

    Mixtures: SAN. VE TİC. LTD., TISSEEL FIBRIN SEALANT VH S/D (FROZEN)
  7. Drug

    Oxymorphone

    go.drugbank.com/drugs/DB01192
    ApprovedVet approved

    On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and abuse risks associated with the product's injectable reformulation. … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    alpha-Tocopherol succinate

    go.drugbank.com/drugs/DB14001
    ApprovedNutraceuticalVet approved

    , males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males … = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120].

    Synonyms: d-alpha-Tocopherol acid succinate, Tocopheryl acid succinate,D-alphaMixtures: Dialyvite Supreme D, Vitamin E 400 Iu With Selenium, Vitamin C & Manganese
  9. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. … This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing toxic side effects.

  10. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood pressure.

    Mixtures: ENALADIL-DUO, ENALADIL-DUOCategories: P-glycoprotein inhibitors