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Displaying results 6891 - 6900 of 10000 in total
  1. Target

    Axin-1

    go.drugbank.com/bio_entities/BE0003316
    TargetHumans

    Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (PubMed:12192039, PubMed:27098453, PubMed:28829046). Controls dorsoventral p...

    Polypeptides: Axin-1Synonyms: Axis inhibition protein 1
  2. Target

    Pannexin-1

    go.drugbank.com/bio_entities/BE0003719
    TargetTransporterHumans

    Ion channel involved in a variety of physiological functions such as blood pressure regulation, apoptotic cell clearance and oogenesis (PubMed:15304325, PubMed:16908669, PubMed:20829356, PubMed:20944749, PubMed:30918116). Forms anion-sel...

    Polypeptides: Pannexin-1
  3. Target

    Phosphoglucomutase-1

    go.drugbank.com/bio_entities/BE0004461
    TargetEnzymeHumans

    Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate (PubMed:15378030, PubMed:25288802).

    Polypeptides: Phosphoglucomutase-1Synonyms: PGM 1, Glucose phosphomutase 1
  4. Target

    Synapsin-1

    go.drugbank.com/bio_entities/BE0004488
    TargetHumans

    Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (PubMed:21441247,...

    Polypeptides: Synapsin-1
  5. Target

    Galectin-1

    go.drugbank.com/bio_entities/BE0004493
    TargetHumans

    Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylati...

    Polypeptides: Galectin-1Synonyms: Gal-1, S-Lac lectin 1
  6. Target

    Lipocalin-1

    go.drugbank.com/bio_entities/BE0005828
    TargetHumans

    Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocycl...

    Polypeptides: Lipocalin-1
  7. Target

    Copine-1

    go.drugbank.com/bio_entities/BE0009002
    TargetHumans

    Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed:14674885). Involved in the TNF receptor signaling pathway in a calcium-dependent manner (PubMed:14674885). Exhibits calc...

    Polypeptides: Copine-1
  8. Target

    Calcipressin-1

    go.drugbank.com/bio_entities/BE0009008
    TargetHumans

    Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A (PubMed:12809556). Could play a role during central nervous system development (By similarity)

    Polypeptides: Calcipressin-1Synonyms: Regulator of calcineurin 1, Down syndrome critical region protein 1
  9. Target

    Actin-1

    go.drugbank.com/bio_entities/BE0009170
    TargetPlasmodium falciparum (isolate HB3)

    Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm (PubMed:15670824). Polymerizes into shorter and less stable actin filaments compared to ACT2/actin-2; this is thou...

    Polypeptides: Actin-1
  10. Target

    Hemocyanin 1

    go.drugbank.com/bio_entities/BE0010299
    TargetMegathura crenulata

    Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.

    Polypeptides: Hemocyanin 1