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Guanabenz
go.drugbank.com/drugs/DB00629ApprovedWithdrawnGuanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
Synonyms: N-(2,6-DICHLOROBENZYLIDENE)-N'-AMIDINOHYDRAZINE, 2-((2,6-DICHLOROPHENYL)METHYLENE)HYDRAZINECARBOXIMIDAMIDECategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AgonistsAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Synonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidMixtures: ALENDRON-HEXAL 4 WO CAL D, BONEX-D 70 MG / 2800 IU TABLET, 4 ADETDocosanol
go.drugbank.com/drugs/DB00632ApprovedDocosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). … A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV).
Synonyms: 1-Docosanol, Docosan-1-olProducts: Erazaban 100 mg/g CremeDexmedetomidine
go.drugbank.com/drugs/DB00633ApprovedInvestigationalVet approvedAn agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Synonyms: (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole, (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazoleCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AgonistsPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Pemetrexed Krka Page 1/1, SUMITREXED®Dextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnThe levo-isomer appears to exhibit a very limited antitussive effect.
Synonyms: d-PropoxypheneMixtures: Darvocet-N 50, Darvocet-N 100Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Synonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid, L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acidCategories: Vitamin B Complex, Heterocyclic Compounds, 2-RingPirenzepine
go.drugbank.com/drugs/DB00670ApprovedWithdrawnAn antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duod...
Synonyms: 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oneCategories: Heterocyclic Compounds, 2-RingGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[L13571] It is therefore not considered to be a disease-modifying drug. … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: ANTAMIN ® 8 MG, REMINYL ®ER CAPSULAS DE 8 MGAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalAmphotericin B shows a high order of in vitro activity against many species of fungi. … While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B.
Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate Complex