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Displaying results 6981 - 6990 of 10000 in total
  1. Drug

    Xylazine

    go.drugbank.com/drugs/DB11477
    InvestigationalVet approved

    Xylazine is a clonidine analog used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. … [L42675] Xylazine is sometimes used as an adulterant and combined with opioids and recreational drugs; however, it has no antidote, and the use of [naloxone] has no effect on xylazine.[L42675,L42680]

  2. Drug

    AEM-28-14

    go.drugbank.com/drugs/DB17643
    Experimental

    AEM-28-14 is an analog of [AEM-28], an apolipoprotein E mimetic peptide, with a 400 percent greater cholesterol-lowering efficacy and a several-fold increase in drug tolerability. … [L45909] It is being investigated for lipid disorders such as homozygous familial hypercholesterolemia.[L45914]

  3. Drug

    Tunicamycin

    go.drugbank.com/drugs/DB13172
    Experimental

    Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response. … step of glycoprotein synthesis in eukaryotes.

  4. Drug

    Efineptakin alfa

    go.drugbank.com/drugs/DB16395
    Investigational

    This drug is currently being investigated in the areas of oncology, immunology, and infectious disease. … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability.

    Synonyms: NT-I7, Recombinant human IL-7-HYFC
  5. Drug

    Alfaxalone

    go.drugbank.com/drugs/DB11371
    ExperimentalVet approved

    It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. … Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin.

  6. Drug

    Livoletide

    go.drugbank.com/drugs/DB15188
    Investigational

    Livoletide is under investigation in clinical trial NCT03790865 (Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome).

  7. Drug

    Bixalomer

    go.drugbank.com/drugs/DB15200
    Investigational

    Bixalomer is under investigation in clinical trial NCT01115985 (A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers).

  8. Drug

    Gotistobart

    go.drugbank.com/drugs/DB19100
    Investigational

    Gotistobart is under investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors).

  9. Drug

    Gaxilose

    go.drugbank.com/drugs/DB12767
    ApprovedWithdrawn

    Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance.

  10. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)