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Amantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Products: PK MERZ FTA 100MG, PK MERZ FTA 150MGEtoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnEtoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inh...
Mixtures: DOSCOXEL-DUOProducts: ARCOXIA 30MG FTA, ARCOXIA 90MG FTAQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.
Categories: Dopamine D2 Receptor AntagonistsProducts: Van-quetiapine, QUETIAPINA DR. REDDY'SPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
International brands: Kaon Cl, Kaon-CL 10Mixtures: INYECCION DE LACTATO DE RINGER, INYECCION DE CLORURO DE POTASIO EN DEXTROSA AL 5% Y CLORURO DE SODIO 0.9% 20 MEQ/LIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma. … [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer.
Products: CLORHIDRATO DE IRINOTECAN TRIHIDRATO 20 MG/ML, IRINOTEL 40 MG/2 ML IV INFUZYON ICIN KON. COZ. ICEREN FLAKONAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigational[L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Products: Nu-azathioprine, AZATHIOPRIN AL 25MG FTAEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[FDA Label] PPIs such as esomeprazole have also been shown to inhibit the activity of dimethylarginine dimethylaminohydrolase (DDAH), an enzyme necessary for cardiovascular health. … [A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Mixtures: MELOCAM DUO 15/20 TABLETAS, MELOCAM DUO 7.5/20 MG TABLETAS RECUBIERTASProducts: Esomeprazole DR, Esomeprazole Magnesium D/rPitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. … [A181090,A181093,A181096,A181427,A181475,A181538] Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD
Products: LIVAZO 1MG FTA, LIVAZO 2MG FTACapecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.
Synonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamateProducts: XELODA 500MG FTA, ECANSYA 500MG FTALamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Mixtures: ZOVILAM PED DT®, ABACAVIR E LAMIVUDINA DR. REDDY'SProducts: EPIVIR 300MG FTA, LAMIVUDIN TEVA 150MG FTA