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Displaying results 61 - 70 of 47710 in total
  1. Drug

    Pemlimogene merolisbac

    go.drugbank.com/drugs/DB16286
    Investigational

    Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy...

    Synonyms: (actan100), 5 tandem copies of a 21 amino acid fr, Recombinant live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids of the lm acta protein
  2. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.

    Mixtures: RIFAMPICIN 75 MG/ISONIAZID 50 MG/PYRAZINAMIDE 150 MG, RHZ Kid DT (Rifampicin 75 mg, Isoniazid 50 mg and Pyrazinamide 150 mg Dispersible Tablets)Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2A6 Inducers
  3. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]

    Mixtures: ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET, ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Cyanocobalamin

    go.drugbank.com/drugs/DB00115
    ApprovedInvestigationalNutraceutical

    This drug was initially approved by the FDA in 1942 [FDA label]. … Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms.

    Mixtures: Prim - Royal P.M.T., BENEDAY 250/250/1/300 MG 50 ENTERIK KAPLI TABLETInternational brands: Cobolin-M
  5. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

    Mixtures: DAYCOLD-HOT 500/10/15/100 MG SAŞE ,10 SAŞE, DAYCOLD-HOT 500/10/15/100 MG SAŞE ,20 SAŞEProducts: ESTER-VIT 500 MG FILM KAPLI TABLET, 50 ADET, VITAMIN C 50 MG (TABLET)
  6. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).

    Products: LEVETIRACETAM BAS 100MG/ML, LEVETIRACETAM GL100 1ML AS
  7. Drug

    Cendakimab

    go.drugbank.com/drugs/DB18427
    Investigational

    Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL-13 (INTERLEUKIN 13, IL-13)), HUMANIZED MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN HUMANIZED (1-453) (VH (HOMO SAPIENS IGHV2-5*08 (80.6%) -(IGHD) -IGHJ4*01 (100%, )) (10.7.15) (1-123) -HOMO SAPIENS IGHG1*03V, G1M3>G
  8. Drug

    Iopromide

    go.drugbank.com/drugs/DB09156
    Approved

    It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs

    Synonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamideProducts: RAVİSTU 300 MG I/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 50 ML, İOPOLİMİD 370 MG I/ML ENJEKSİYONLUK ÇÖZELTİ, 50 ML
  9. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA.

    Mixtures: Orabloc 40 mg/ml + 10 Mikrogramm/ml Injektionslösung, Sopira Citocartin 40 mg/ml + 10 Mikrogramm/ml InjektionslösungCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  10. Drug

    Metamizole

    go.drugbank.com/drugs/DB04817
    ApprovedInvestigationalWithdrawn

    [A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis … [L42975] In 1963, metamizole was withdrawn from the Canadian market and banned in the UK, France, Sweden, Norway and Australia.

    Mixtures: DIPIRONA 300 MG + ISOMETEPTENO 50 MG + CAFEINA 30 MG GOTAS, DIPIRONA SODICA 300 MG/ ISOMETEPTENO CLORHIDRATO 50 MG / CAFEINA 30 MG GOTASCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A Inducers