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Displaying results 691 - 700 of 10000 in total
  1. Drug

    Carbinoxamine

    go.drugbank.com/drugs/DB00748
    Approved

    The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many … This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.

  2. Drug

    Golodirsen

    go.drugbank.com/drugs/DB15593
    ApprovedInvestigational

    [L10755,L10758] Golodirsen was initially rejected for FDA approval over concerns about its potential renal toxicity, however, clinical trials did not show significant toxicity.[L10755] … Continued approval of this drug will depend on the results of clinical trials that confirm its clinical benefit.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Diphenoxylate

    go.drugbank.com/drugs/DB01081
    ApprovedIllicitInvestigational

    It has little or no analgesic activity.

    Mixtures: SUN-DIANOX TABLET, SUN-DIANOX TABLETCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. … The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the

    Mixtures: EZETIMIBE E SIMVASTATINA SUN, EZETIMIBE E SIMVASTATINA SUNProducts: Ag-ezetimibe, EZETIMIBE EG
  5. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized. … of heart failure, and hospitalization.

    Mixtures: SEVIKAR HCT 40 mg/5 mg/25 mg Filmtabletten, SEVIKAR HCT 40 mg/10 mg/25 mg FilmtablettenCategories: Agents Acting on the Renin-Angiotensin System
  6. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160]. … [L43942] Other forms of pentoxyverine citrate continue to be marketed.

    Products: PENTOXYVERIN AL 1.35 MG/ML, SILOMAT GG REIZH PENTOXYVE
  7. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.

    Mixtures: PIPERACILINA 4000 MG Y TAZOBACTAM 500 MG, PIPERACILINA 4.0 G + TAZOBACTAM 0.5 GCategories: combinations of penicillins, Penicillin G
  8. Drug

    Abaloparatide

    go.drugbank.com/drugs/DB05084
    ApprovedInvestigational

    [L740] It was first approved by the FDA on April 28, 2017,[A256748] for the treatment of osteoporosis in postmenopausal women and is also used to increase bone density in men with osteoporosis. … Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) [A256778] and an agonist at the parathyroid hormone type 1 (PTH1) receptor.

  9. Drug

    Penicillium chrysogenum var. chrysogenum

    go.drugbank.com/drugs/DB10439
    Approved

    Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  10. Drug

    Vimseltinib

    go.drugbank.com/drugs/DB17520
    ApprovedInvestigational

    [L52230] It is highly selective, with a >500-fold selectivity for CSF1R over its nearest off-target kinase. … in a lower risk of off-target effects, including hepatotoxicity.