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Protamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalAs a consequence, whenever protamine sulfate use is clinically considered, careful consideration must be given as to whether the use of the agent could decrease the safety of the procedure or worsen the … Since it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps
Rosiglitazone
go.drugbank.com/drugs/DB00412ApprovedInvestigationalIt is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl).
Triclocarban
go.drugbank.com/drugs/DB11155ApprovedIn 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal … Triclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly effective against Gram-positive bacteria such as *Staphylococcus aureus*.
Calcium citrate
go.drugbank.com/drugs/DB11093ApprovedInvestigationalCalcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Ifosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIt is active as an alkylating agent and an immunosuppressive agent.
Calcitonin porcine
go.drugbank.com/drugs/DB13189ExperimentalThe first commercially available preparation in Britain was porcine calcitonin (brand name Calcitare).
Firocoxib
go.drugbank.com/drugs/DB09217ExperimentalVet approvedIt currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S.
Fimasartan
go.drugbank.com/drugs/DB09279InvestigationalFimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand name _Kanarb_ by Boryung Pharmaceuticals.
Daprodustat
go.drugbank.com/drugs/DB11682ApprovedInvestigationalAs a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces erythropoiesis. … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for anemia caused by chronic kidney disease in patients on dialysis.
Carbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationalThe FDA classifies this drug as permitted as a food additive in the packaging and preparation of food products, while following the federal code of regulations [L2531]. … The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish.