Firocoxib

DB09217ExperimentalVet approvedSmall molecule

Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first... Firocoxib is not intended or approved for use in human medicine.

Mechanism: Pharmacologically active on Prostaglandin G/H synthase 2
Curator reviewed
Primary indication: Used for the treatment of pain inflammation and fever in horses and dogs.Curator reviewed
Formula / weight: C₁₇H₂₀O₅S · 336.4 g/mol (avg)
Code names: ML-1,785,713

Resolves to

Compound

UNIIY6V2W4S4WTCAS189954-96-9ChEMBLCHEMBL69998ChEBI76136PubChem208910KEGGD03712

Clinical / RWD

RxNorm473298PharmGKBPA166049194

Structure

InChIKeyFULAPETWGIGNMT-UHFFFAOYSA-NSMILESCC1(C)OC(=O)C(OCC2CC2)=C1C1=CC=C(C=C1)S(C)(=O)=O

Targets

P35354PTGS2Q8SPQ9Prostaglandin G/H synthase 2

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,410Drug interactionsStructured to mechanism, not free text

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Firocoxib, and which of those have an active Phase 3 trial?

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