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Displaying results 691 - 700 of 912 in total
  1. Drug

    AVB-001

    go.drugbank.com/drugs/DB18452
    Investigational

    AVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native human IL-2 cytokine

  2. Drug

    Thyme

    go.drugbank.com/drugs/DB10983
    Approved

    Thyme allergenic extract is used in allergenic testing.

    Mixtures: Oil
  3. Drug

    Deuruxolitinib

    go.drugbank.com/drugs/DB18847
    ApprovedInvestigational

    Deuruxolitinib is a deuterated form of ruxolitinib that selectively inhibits Janus kinases (JAK) JAK1 and JAK2. Deuteration allows the drug to circumvent extensive oxidative metabolism around the cyclopentyl ring, which increases the dur...

    Categories: Bile Salt Export Pump Inhibitors
  4. Drug

    BJ-001

    go.drugbank.com/drugs/DB18585
    Investigational

    BJ-001 is a recombinant human interleukin-15/IL-15 receptor alpha complex with linked integrin-binding motif.

  5. Drug

    Belnacasan

    go.drugbank.com/drugs/DB05507
    Investigational

    VX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198). VX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it block...

  6. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often com...

    Mixtures: Ti-uva-B, Ultra Sun Protection Lotion TiProducts: Dark Tanning Oil, Sunscreen Oil SPF 2
  7. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption....

    Mixtures: Ratio-ipra Sal Udv
  8. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.

    Mixtures: VIL-Rx, Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap
  9. Target

    Serine/threonine-protein kinase SIK1

    go.drugbank.com/bio_entities/BE0004757
    TargetHumans

    Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1,...

    Synonyms: Salt-inducible kinase 1
  10. Drug

    Amorolfine

    go.drugbank.com/drugs/DB09056
    ApprovedWithdrawn

    It is approved for sale over the counter in Australia and the UK (recently re-classified to over the counter status), and is approved for the treatment of toenail fungus by prescription in other countries